Multidimensional Analysis of the Effects of Clonal Hematopoiesis on Heart Failure Progression

Publications

Read the last publications of the project

Identification of Clonal Hematopoiesis Driver Mutations through In Silico Saturation Mutagenesis

Santiago Demajo, Joan E. Ramis-Zaldivar, Ferran Muiños, Miguel L. Grau, Maria Andrianova, Núria López-Bigas, Abel González-Pérez.

Cancer Discov (2024) 14 (9): 1717–1731.

Colchicine prevents accelerated atherosclerosis in TET2-mutant clonal haematopoiesis

Zuriaga MA, Yu Z, Matesanz N, Truong B, Ramos-Neble BL, Asensio-López MC, Uddin MM, Nakao T, Niroula A, Zorita V, Amorós-Pérez M, Moro R, Ebert BL, Honigberg MC, Pascual-Figal D, Natarajan P, Fuster JJ.

Eur Heart J . 2024 Aug 30:ehae546

Unidirectional association of clonal hematopoiesis with atherosclerosis development

Miriam Díez-Díez, Beatriz L Ramos-Neble, Jorge de la Barrera, J C Silla-Castro, Ana Quintas, Enrique Vázquez, M Ascensión Rey-Martín, Benedetta Izzi, Lucía Sánchez-García, Inés García-Lunar, Guiomar Mendieta, Virginia Mass, Nuria Gómez-López, Cristina Espadas, Gema González, Antonio J Quesada, Ana García-Álvarez, Antonio Fernández-Ortiz, Enrique Lara-Pezzi, Ana Dopazo, Fátima Sánchez-Cabo, Borja Ibáñez, Vicente Andrés, Valentín Fuster, José J Fuster

Nat Med . 2024 Aug 30

Clonal haematopoiesis and cardiac arrythmias: rhythm-altering mutations

María A Zuriaga, Domingo Pascual-Figal, José J Fuster

Eur Heart J . 2024 Mar 7;45(10):806-808

Meteorin-like protein is associated with a higher risk profile and predicts a worse outcome in patients with STEMI

Gemma Ferrer-Curriu, Ferran Rueda, Elena Revuelta-López, Cosme García-García, Pau Codina, Carolina Gálvez-Montón, Santiago Roura, Alberto Aimo, Michele Emdin, Anna Planavila, Antoni Bayés-Genís

Rev Esp Cardiol (Engl Ed) . 2023 Nov;76(11):891-900

Personalizing anti-inflammatory therapy in heart failure: A new way

Domingo Pascual-Figal, Jose Javier Fuster, Antoni Bayes-Genis

Eur J Heart Fail . 2023 Nov;25(11):1933-1935

Clonal Hematopoiesis in Patients With Atherosclerotic Cardiovascular Disease: One Step Closer to the Clinical Scenario

José J Fuster, Benedetta Izzi

JACC. 23 May 2023; 81(20):2010-2012

TP53- mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease

Seyedeh M Zekavat, Vanesa Viana-Huete, Nuria Matesanz, Saman Doroodgar Jorshery, María A Zuriaga, Md Mesbah Uddin, Mark Trinder, Kaavya Paruchuri, Virginia Zorita, Alba Ferrer-Pérez, Marta Amorós-Pérez, Paolo Kunderfranco, Roberta Carriero, Carolina M Greco, Alejandra Aroca-Crevillen, Andrés Hidalgo, Scott M Damrauer, Christie M Ballantyne, Abhishek Niroula, Christopher J Gibson, James Pirruccello, Gabriel Griffin, Benjamin L Ebert, Peter Libby, Valentín Fuster, Hongyu Zhao, Marzyeh Ghassemi, Pradeep Natarajan, Alexander G Bick, José J Fuster, Derek Klarin

Nat Cardiovasc Res . 2023 Jan 16:2:144-158

Discovering the drivers of clonal hematopoiesis.

Pich O, Reyes-Salazar I, Gonzalez-Perez A, Lopez-Bigas N.

Nature Communications. 2022 Jul 23.

Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome.

Díez-Díez M, Amorós-Pérez M, de la Barrera J, Vázquez E, Quintas A, Pascual-Figal DA, Dopazo A, Sánchez-Cabo F, Kleinman ME, Gordon LB, Fuster V, Andrés V, Fuster JJ.

Geroscience. 2022 Jun 25.

Clonal hematopoiesis and cardiovascular disease in cancer patients and survivors

José J Fuster

Thromb Res . 2022 May:213 Suppl 1:S107-S112

Clonal hematopoiesis in cardiovascular disease and therapeutic implications

Alan R Tall, Jose J Fuster

Nat Cardiovasc Res . 2022 Feb;1(2):116-124

Prevalence and characteristics of clonal hematopoiesis in heart failure.

Palomo L, Santiago-Vacas E, Pascual-Figal D, Fuster JJ, Solé F, Bayés-Genís A.

Rev Esp Cardiol (Engl Ed). 2021 Nov;74(11):996-999.

The evolution of hematopoietic cells under cancer therapy.

Pich O, Cortes-Bullich A, Muiños F, Pratcorona M, Gonzalez-Perez A, Lopez-Bigas N.

Nature Communications (2021) 12, 4803

DNA methylation biomarkers of myocardial infarction and cardiovascular disease.

Fernández-Sanlés A, Sayols-Baixeras S, Subirana I, Sentí M, Pérez-Fernández S, de Castro Moura M, Esteller M, Marrugat J, Elosua R.

Clin Epigenetics. 2021 Apr 21;13(1):86.

Clonal hematopoiesis and risk of progression of heart failure with reduced left ventricular ejection fraction.

Pascual-Figal DA, Bayes-Genis A, Díez-Díez M, Hernández-Vicente A, Vázquez-Andrés D, De La Barrera J, Vazquez E, Quintas A, Zuriaga MA, Asensio-López MC, Dopazo A, Sánchez-Cabo F, Fuster JJ.

J Am Coll Cardiol. 2021 Apr 13;77(14):1747-1759.

Differences in the Interleukin-1β/Soluble ST2 Interplay Between Acute and Chronic Heart Failure.

Revuelta-López E, Lupón J, Lax A, Pascual-Figal DA, Bayés-Genís A.

J Cardiovasc Transl Res. 2020 Oct;13(5):864-866.

Epitranscriptomics in Hematopoiesis and Hematologic Malignancies.

Rosselló-Tortella M, Ferrer G, Esteller M.

Blood Cancer Discov. 2020 Jun 22;1(1):26-31.

DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues.

Gallego-Fabrega C, Cullell N, Soriano-Tárraga C, Carrera C, Torres-Aguila NP, Muiño E, Cárcel-Márquez J, de Moura MC, Fernández-Sanlés A, Esteller M, Elosua R, Jiménez-Conde J, Roquer J, Montaner J, Krupinski J, Fernandez-Cadenas I.

Oncotarget. 2020 Mar 10;11(10):905-912.

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice.

Fuster JJ, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu CL, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AAB, Cooper MA, Andrés V, Hirschi KK, Martin KA, Walsh K.

Science. 2017 Feb 24;355(6327):842-847.